For thousands of years two distinct cultures evolved unaware of one another's existence. Separated by what one culture called The Great Sea and known to the other as the Atlantic Ocean, the course of each culture's future changed irreversibly four hundred years ago. In 1620 the Mayflower delivered 102 refugees and fortune seekers from England to Cape Cod, where these two cultures first encountered one another. The English sought religious freedom and fresh financial opportunities. The Natives were recovering from the Great Dying of the past several years that left over two-thirds of their people in graves. How would they react to one another? How might their experience shape modern cross-cultural encounters?